Xencor, Inc., a clinical stage biopharmaceutical company, focuses on the discovery and development of engineered monoclonal antibody and cytokine therapeutics to treat patients with cancer and autoimmune diseases. The company provides Sotrovimab that targets the SARS-CoV-2 virus; Ultomiris for the treatment of patients with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome; and Monjuvi for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma. It develops Plamotamab, a tumor-targeted antibody, which is in Phase I clinical trial to treat non-Hodgkin lymphoma; Vudalimab, a bispecific antibody, which is in Phase II clinical trial to treat metastatic castration-resistant prostate cancer and other solid tumor types; and Tidutamab that is in Phase II clinical trial to treat neuroendocrine tumors. The company is also developing XmAb306, which is in Phase I clinical trial to treat solid tumors; XmAb104 and XmAb841, which are in Phase I clinical trial to treat patients with selected solid tumors; XmAb564 that is in Phase I clinical trial to treat autoimmune diseases; AMG 509, which is in Phase I clinical trial to treat prostate cancer; XmAb819 for patients with renal cell carcinoma; and Novartis XmAb. It develops VIR-3434, which is in Phase II clinical trial for patients with hepatitis B virus infection; VIR-2482 that is in Phase 1/2 clinical trial to trat influenza A; VIR-7832, which is in Phase 1b/2a trial to treat mild-to-moderate COVID-19; and BMS-986414 + BMS-986413 is in Phase 2/3 NIH ACTIV-2 trial in treating COVID-19. The company develops AIMab7195 to reduce blood serum levels of IgE that mediates allergic responses and allergic disease; Obexelimab to treat autoimmune disease; and Xpro1595 to treat patients with Alzheimer's disease, mild cognitive impairment, and depression. It has a license agreement with Caris Life Sciences. Xencor, Inc. was incorporated in 1997 and is headquartered in Monrovia, California.

生物技术

Ms. Jennifer  Sandoz

Senior VIce President of Human Resources

Mr. Bart Jan Cornelissen

Senior Vice President & Chief Financial Officer

Mr. Charles  Liles

Associate Director and Head of Corporate Communications & Investor Relations

Dr. Bassil I. Dahiyat Ph.D.

Co-Founder, Chief Executive Officer, President & Director

Ms. Celia E. Eckert J.D.

Senior Vice President, General Counsel & Corporate Secretary

Dr. Jeremy  Grunstein Ph.D.

Senior Vice President of Business Development

Dr. Nancy  Valente M.D.

Executive Vice President & Chief Development Officer

Dr. John R. Desjarlais Ph.D.

Executive Vice President of Research & Chief Scientific Officer

Mr. Kirk  Rosemark RAC

Senior Vice President of Regulatory Affairs & Quality Assurance

Mr. Eric P. Kowack

Senior Vice President of Program Leadership & Alliance Management

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Xencor, Inc.

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